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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad20a891c604a6a5ad1f8b3cd790ef87d46d242f87f16d198664a609da9ae56' 
  AND token = 'CzXZYfGoukOCou9+Z8MNUeAzus7xtcLW05nHNvdi6AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}