SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccbd048f8dce1b5071a8cb579f15a59e7d1f0d00b92882cbff4819f3715eefac' 
  AND token = 'PFKAWY45e+Kz2AW//S0gvhGnDSlKzUriEV7AlivahSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}