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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '686ffa18352c2c76522a85f2d59d0b1ed21c4cca89f819b7ba24425175ef44c4' 
  AND token = 'atxis5wmxW/ZmW2aC2YLhyLjoYeN55w1BwyI2n6iD+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}