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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '334706b8f1cfe1bd534e7d3b086b09209af87007abf02bc1cbe29cc106adb8c0' 
  AND token = 'CGlgtn49DQq3pd/nEO/ReazbB1Uev20GVJxVAYWUNIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}