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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb9856307c346ad6a42224d76d692149249c7db42e5b96dab37a900470c6e6e' 
  AND token = 'oA0YpWIOVezZ2x7dgCC/1H7CrgNhWpnvgKYaKZCuJMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}