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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fdd618bd659a7596f749cdd5c7eade2320d4b3eee87e28b92d3feee1175e7a5' 
  AND token = 'eWmATKuhI+CWxuLszVhM0pA1noD/REx9aXdkEkAUbMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}