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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ef7e3a99a97fb326411981a5c13077504098c2eea348c8b749c8b0a1b5553a' 
  AND token = 'y/PlUw1Atet4Z5XyzNAKdxrkqD82bMyVJNz/GINVvgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}