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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52173047f5b6b14ca33b6c722bd7fc018d3d15e3aaca0905ff9f7cbde44dd28b' 
  AND token = 'AWDW5FRz3zlqZA/j8495/7iDcMMiRMBDBb4UqSVZ4vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}