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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153aaa145ada7598fea46cb060ce0da07f4e033b93ac6a8cc362fed5ec9b08a0' 
  AND token = 'TvEOQl2P09FXonJKtxNxlP7VwDYibuAH2LNLB1AILaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}