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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce5ffd73a005cba48f35dce24b1503e6dd26e2399551e161e4637541d0e22eb8' 
  AND token = 'nvS18q0hvdBcKA8Fk91ZkZUx2A4XYIM6DboKAyRq0io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}