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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46dc66cacc466d73b1661f0c5f1c3fb115ea4da1b789d156b18270482c33648f' 
  AND token = 'NaCyqpbc48C5v6ewsrel+KkXjyMIo5htb12hF6ni2OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}