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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f48e0f80e6af5e1ea35f85823417252e8e7413cb4282abc0eb67a2f192455a59' 
  AND token = 'pxz77NGKeC6z0VPOzSl7bCitBRK7klpresBYW3owbOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}