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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19d5693ced21823550f7b9b03d7c989734591f0a6f03ce6d313960c72da5a7e1' 
  AND token = 'oYNoNlhy2XfbuIb3jHaSmL5BEfZYWRhP8i+PjVn2wbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}