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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ab964deb26603a78ac9989f4714c4ee4e899591521c12b0ee38848e5808529e' 
  AND token = '/N/xdx7Er3aU2o60oIapCx7h20vw22CUT8FqP5gyAtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}