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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e7f6391f6f25a43befea6a7f5c4bb19393dace22dbadb28c95e57be8e2e065' 
  AND token = 'GIMOZUBBRJQmWdPt7ZDaE16n8oriwCBLDtIrxcshOmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}