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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a856a711345b0a0fba7f6d7d3bef534806f5c0c72ee2627188cf22b8548eae2' 
  AND token = 'zE0mqElPHFxcvu8V6BDqaMFmwZ+nq9DvP2qo3PtfBvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}