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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294ac29a82e55c46b8e7a7f7e637e23146d1548ca163383b2685d9e916138b81' 
  AND token = 'yB3Wp5sCxZEcM+PaRexfJFOG8t7iMSY/E6ZNTzB/edM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}