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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae24fcb71d94f21bcd4eea60682223fcc1b66efb1493545190e09fb58008fff5' 
  AND token = 'CttFh/Y/Y0KamArKdIv1b1tXZbeqXl0pfyHIN2InQ9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}