SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c1465780bc552f4a6f444304378cf88dccdb333406c546a6747383091430b7' 
  AND token = 'zjFHrPxRBmnlk5e+lkd3R6lCWVp0860VkJL5RgUdZi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}