SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9ca6d134219b327c73f0a0ed8f30b7f4ac7b8947a84f87cfe583f4da21f548f' 
  AND token = 'Z6sW0o5dvsMEz9meWWLiGYtZH5BOVGN9vI8sthLiWIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}