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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78a43dd91b9b652561b17081bb9471bc37bfcb66e81b257761ecdb84b1875c4' 
  AND token = 'R9YRPd3lIbEavpmJV7BGfvLyHnLtk/x4qnQfdFquaWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}