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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '975387f6820c103b8b8416133c9fe22b4f3aeefe277bd80b460662bf18a538f6' 
  AND token = '1fWQtnmb4uYxxVE6OxhlVulJzLSYj7dV46YEo9qqK6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}