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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e90d41c060071c1b7b0cccb4a2f7852c205c83d7a90b8590112b3c41c9b068' 
  AND token = 'FAv7nfvSHLJim3/UmOrSjoz+TGyCMU+P6lr2IGvmN2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}