SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea47fbff4e3c94bf62de1b5bda8a5b6437dc218e515f71ee068b2a433db0625' 
  AND token = 'ZjzWpE6N/pg+z0+ScL4B7GfJerHSAt1XHg36ld2siqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}