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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dbe7fec533975e143dc6e6c0b7343f37b1fc182951a424c3245adc20a1fa359' 
  AND token = 'Wy/3ssZHXRFGLfiaAInT3XE/lTEzNVfItV51rrXX09Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}