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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ac399f5f016a4fb968b4d02cbe3a97991a7e8931f59c0938c985a04fec0d3a4' 
  AND token = 'ZWwUrGNr9kMeyj2YPINgKGADvt67xu9ABdDtPiVyP9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}