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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7644e3f7d5a2001c0f54c7276d600037897e5ad13622f62bff9f1990a3ba6479' 
  AND token = 'JqIdj0DhryEKA+ZGwRS4l0mpkQTSNq6WO13LXYf82nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}