SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec2337bd308eee9890208f4246573159d4ad7ff8cbae79cc627a0bfb5a3b8ed3' 
  AND token = 'wIplkajyJ9Zyc9Y3OIW6GDb+fMiwd82n2D4MEbjQhL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}