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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e580da82d4e6b2221bc1ccfec7acbd439fca9b702b03dd7fb78f0a362817961c' 
  AND token = 'bJA9yObkJn4T5n2P0FFgadrRjUK32kmvXwc4N4F49+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}