SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b682e1a8462f09bdee2ca28dae0af7fdd33c437c7c135fe8911c4ebce0b530' 
  AND token = '1mwB3NzY8o/NmUb4s0leEDxsq1XPG/ZWterOw9Ud58A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}