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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a464cde0f07e86c691b2c4b7227f708388d3661820309a8b91b1624c5ae6ab5' 
  AND token = 'n4psSMoPq4MZwtp9d5N8VeioWok1IxCV5q/guje8h5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}