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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfb7499dc124506aefc0d9bf94cb5f5032749e651b019135e0d5f1abd83bfff3' 
  AND token = 'xq94L1DBEUSXaB/xxbrv1VXWTK2QiB5NRnq2baOR7Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}