SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0492c92cd78170e3a38e7bca250ce45e6a01705ab8b395a53f718394e1cc644' 
  AND token = 'mD3W15f9l9TQkoR7z3nTkdhdSY+IIVQd/J8Y0wbl6u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}