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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5842e5bc5a9fb68132b353d13ebc47ca0df518858122e33761f1427c9fd6445' 
  AND token = 'SXDn1g6ZGD1tg3g4Pp12cRL7r1C1bO3ugxN/AhHCecE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}