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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a1fabe69f37869e79872e02f57a9829cd6e99099c6d08c96e101874a38b0c42' 
  AND token = '4m6VzPHdHkLZO+3V2cK+8xm/BgsnJoNr77NFgvlwcTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}