SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1c7f315ab032ddafe148ac6a623168d08f89a441d7dd3a9697331aa7358c11' 
  AND token = 'Az/oQkuE/mASC7Tg9FxTzqJepC1zeWTaYjk5+o/FDA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}