SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9e2d36a604c3264f6152d1b37430103cf1070935d47f09d34743449d3813819' 
  AND token = 'N3ggMW5AjD1NPgr8dOjfwOW/4ZEyPRdcCayjoC/td9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}