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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165c723ed980d59084ba5edafff214079f78602388ec57968c4ad3c0a420cf6e' 
  AND token = '6cWpe4LXd3VRoVVvBQ7eRvTZMD1vXR5pL/X4ep2zwBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}