SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b2366566b279a80d5a1afbd9c8d46a5a3e0c89fda80468a9ff703cff6ef2345' 
  AND token = '11fsneLKCnyICg30qokhURuNyF2inMD3Fezx6kgo90s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}