SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f285545c83aa4ef99099f6e3cd70a9ffe547091acd2836328597fba7bbd7c294' 
  AND token = 'uMw4RTTtdJlPk9fnbvUV4RPePhdqYVBTizv/S8i4Oo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}