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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c57eda8342f0d91b869028f53d4e005fdd789a421ef85bd1d36f8b74f0e04a16' 
  AND token = 'TF1qyef+TAQsUvteo4EJ62xh56I0kjTpKs25Wv1AZOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}