SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3775fcbcf5e20b92430b9b0a867de10aaf2c69fef6d8b7fdcb551c32ee352e3c' 
  AND token = 'HK+uAmanAZJs5lAXrtkrsfWZ3zSsqwmA6g8i182Vq/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}