SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '770421cb3593e4d2e3235bef3cd5afbcb6b0512846d4b5061d3fca9fcf6f78e4' 
  AND token = 'YLco9keDk1IBQTtRj0l84Hh1318lcQiTH0F+VRoagm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}