SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c59fd61b4b8df8ce3d93b697f0f8b74e2388b462db69eeb35cba0e600f5241' 
  AND token = 'UfXSYxn6lUzLFqQaR3KoHiu2n8tKJ497xVJKNUaists=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}