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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d10d0e96599cf164dcafdca49b0c329e52b47b7008958268ce67ba7f7e69a30' 
  AND token = 'BLnFH1/NAnAfHW4Rv2g2avyKCGbz2OXJ0fXMkNm8bQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}