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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13d47cb14d3d63e15552a07da60206c3b91df1ef48bfef0fca510022b3c7eef9' 
  AND token = '0x2pgrtP9M7cuJowfBhWtqujpyr79w3JwXD1dVMnU9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}