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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca70e2e38b765a7268a35933fa0056fba2d14250598fab0cf1a16d9e6c0465c' 
  AND token = 'E8fr/0g7R0aMuCszAkynwRksbfX7S/SfAlN+FoCY+AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}