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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6308d2b77a674dbb8950b5b0bfcc7bf2710f906be0890f436a006d65ba10c10' 
  AND token = 'BleV5rShSh8ZBf37sq2ldadvLurBBH1geEMLn2FsS8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}