SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8436a976e11c91e73fb352f435716d8563171ce4fdea9eafe8e37c0b887a6f10' 
  AND token = 'lZD9DZ+4hHQriLQ2vEAubEUHGro9gcGIk8CDWbxOd5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}