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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4dcaaed1f4b5b61014feb1e94a8f11ed1275177156d28bc182509c9cf07af71' 
  AND token = 'onWGmLS0Mf3UKfyOL53D6WrtrJYKRkustJ1vm6E9Eck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}